ES031000: 4-Methylumbelliferyl α-N-glycolylneuraminic acid Pack Size:1 mg α-D-Gal-Butyl-Carboxylic Acid

α-D-Gal-Butyl-Carboxylic Acid

The sialic acid carboxyl is protected as a methyl ester to prevent side reactions during synthesis

H-Thr(β-D-GlcNAc)-OH

used to synthesize peptides modeling early non-enzymatic glycation

Fmoc-Thr(β-D-Lac(Ac)7)-OH

ES031000: 4-Methylumbelliferyl α-N-glycolylneuraminic acid Pack Size:1 mg α-D-Gal-Butyl-Carboxylic AcidC21H25NO12 483. 42 A 4 methylumbelliferyl (MU) glycoside of N glycolylneuraminic acid (Neu5Gc), a sialic acid variant carrying an extra hydroxyl on the N acyl group and found in most mammals but not normally in humans. Used as a fluorogenic substrate for sialidases (neuraminidases) with selectivity or preference for Neu5Gc containing sialosides; sialidase catalyzed cleavage of the glycosidic bond releases free Neu5Gc and 4 methylumbelliferone. 4