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Fmoc-L-Ser((Ac)3-β-D-Xyl)-OH
3-triazole linkages without a copper catalyst
5-dihydro-5-oxo-1
enabling enzymatic chain extension
α-D-Man-Et-NH2
PE142000: α-GalNAc-PEG4-Acid label-new Fmoc-L-Ser((Ac)3-β-D-Xyl)-OHC17H31NO11 425. 43 An D N acetylgalactosamine (GalNAc) ligand equipped with a terminal carboxylic acid through a hydrophilic PEG4 spacer. The carboxylic acid can be activated to NHS, sulfo NHS, or pentafluorophenyl esters and reacted with amine functionalized platforms or lysine residues on proteins and peptides to form amide bonds. This compound enables the construction of hepatocyte targeted therapeutics and research tools that exploit the
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