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To clarify the mechanism, immunohistochemical and immunofluorescence staining analyses were conducted on the articular cartilage tissues of each group

This aligns with human studies linking high cysteine levels to obesity, neurological disorders and cardiovascular diseases 55,56,57,58,59

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Study of curcumin immunomodulatory effects on reactive astrocyte cell function

GLP-1 agonists enhance insulin secretion from pancreatic beta cells only when blood glucose levels are elevated, a mechanism termed "glucose-dependent insulinotropic action." This physiological approach reduces the risk of hypoglycemia compared with sulfonylureas or exogenous insulin, though the risk increases when GLP-1 agents are combined with insulin or sulfonylureas, potentially requiring dose adjustments of these medications