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In sym33-3 nodules, GSH levels were comparable to those of wild-type, while the hGSH content was higher, leading to a decrease in the GSH:hGSH ratio

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The "timing hypothesis" or "critical window" hypothesis, now supported by substantial mechanistic and clinical data, proposes that estrogen's cardiovascular protective effects are contingent on initiating therapy while vascular endothelium remains estrogen-responsive, generally within ten years of menopause onset or before age 60 [8]

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Researchers have had trouble getting people to eat even 20 grams, so anything more would likely result in excessively unpleasant taste, due to the bitterness of the leaves. Secondly, the nutritional claims in these papers are adapted from Fuglie, which is evidently a lay publication