Il est utilis dans le traitement et la prvention de la carence en vitamine B12 chez les patients prsentant des affections telles que :_ Anmie addisonienne (prareuse) Malabsorption Gastrite atrophique Traitement prolong avec la metformine La prolifration bactrienne de l'intestin grle (SIBO) gastrectomie totale ou partielle Infection par le parasite poisson Diphyllobothrium latum infection Helicobacter pylori Dysfonction pancratique Cancer du pancras ou des intestins Carence alimentaire (par exemple, mauvaise nutrition ou rgime vgtalien) Dficience en transcobalamine II Il est galement utilis dans le cadre du test d'absorption de la vitamine B12 (test de Schilling)
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Proposed mechanisms include: Enhancing cellular communication Supporting local growth factor expression Modulating nitric oxide pathways for circulation While promising, its important to note that human trials remain limited , and more research is needed before drawing definitive conclusions
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