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Endoplasmic reticulum stress, obesity and diabetes

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TCF7L2 Variants Are Associated with Increased Proinsulin/Insulin Ratios but Not Obesity Traits in the Framingham Heart Study. Diabetologia, vol

For the chromatographic metabolite separation, the Vanquish UPLC systems were coupled to a Q Exactive HF (QE-HF) mass spectrometer equipped with HESI (Thermo Fisher Scientific, Waltham, MA)

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Still, as the problem worsens from malabsorption, it can lead to diarrhea as a symptom of B12 deficiency anemia