While the research on GLP-1 medications and mental health is still evolving, changes in mood that coincide with starting or changing the dose of these medications are worth taking seriously
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The COR-I trial, involving 1,742 participants over 56 weeks, demonstrated 6.1% average weight loss with Contrave versus 1.3% with placebo (Greenway et al., Obesity, 2010)
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Patients were grouped based on whether they regained weight, maintained their weight loss, or experienced further weight reduction
Semaglutide (Ozempic and Wegovy), along with other GLP-1 medications, works by mimicking a naturally occurring hormone in your body called glucagon-like peptide-1 (GLP-1)
