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Under hypoxia, the membrane from excitatory neurons hyperpolarizes, associated with an outward leak current and increased resting conductance at the holding potential [261]

Incorporating these models into practice may enable early interventions and guide public health measures to alleviate the negative impacts of environmental variables on male reproductive health (147)

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For women, supplementation is often recommended for at least 90 days before trying to conceive to ensure nutrient stores are stable at the time of conception, particularly for folate and other pregnancy-critical micronutrients

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