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*Correspondence: Changgang Sun, [email protected] These authors have contributed equally to this work and share first authorship This article was submitted to Cellular Biochemistry, a section of the journal Frontiers in Cell and Developmental Biology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

This can complement other therapeutic approaches and contribute to a more comprehensive management plan

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Furthermore, research was published explaining how human plasma DSIP decreases at the point of sleep regardless of the timing of the sleep, i.e, a persons usual sleep time, or a later sleep time, natural DSIP still decreased

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