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Antioxidant activity of beta-blockers: an effect mediated by scavenging reactive oxygen and nitrogen species

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Thus, it seems logical that stressed erythrocytes should be cleared from circulation before hemolysis occurs to avert proinflammatory and highly detrimental lytic destruction

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10.1038/ki.2012.240 89 KimuraT.TakabatakeY.TakahashiA.KaimoriJ.MatsuiI.NambaT.et al (2011)

(2020) demonstrated that insulin directly inhibits gluconeogenesis in isolated PT through IRS1/AKT2/mTORC1/2, and that mTORC1 positively regulates insulin signaling (Nakamura et al., 2020)