This is particularly relevant given that obesity and T2DM themselves are risk factors for pancreatitis.44,45 Additionally, the prescription of GLP-1RAs is often associated with poor glycaemic control, which could be caused by occult pancreatic diseases.46,47 The treatment selection process introduces intrinsic sources of imbalance and confounding, leading to potential distortions in the results
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Understanding which approach suits each peptide helps design optimal long-term protocols
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The University Hospitals Cleveland Study analyzed 286,000 patient records, finding a 52% increased risk of gastroparesis in patients taking GLP-1 medications
