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2.3 Role of taste receptors in the gastrointestinal hormone secretion Although, we commonly associate TRCs and TASR only to the oral cavity, they are also localized in extra-oral tissues, including the gastrointestinal tract, where they participate in energy homeostasis by modulating enteroendocrine hormone release (GLP-1, GIP, CCK, PYY) and nutrient sensing, thereby influencing gastric emptying and metabolic adjustments (e.g., glycemia) (59, 60)

This helps your system efficiently process glucose, preventing the spikes and crashes that can drive cravings

Mechanism of Action Incretins hormones like GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) are released throughout the day, increasing at mealtimes

Constipation Constipation is another common side effect that, unlike nausea, often persists throughout treatment

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