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Potency loss is minimal (less than 5%) during the first 28 days at correct refrigeration temperature, but accelerates rapidly if the vial experiences temperature excursions above 8C or light exposure

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N-acetyl-L-cysteine enhances the osteogenic differentiation and inhibits the adipogenic differentiation through up regulation of Wnt 5a and down regulation of PPARG in bone marrow stromal cells

Reconstituting with more water creates a lower concentration with larger, easier-to-measure volumes but the vial runs out faster

Indeed, increased E2 levels among overweight and obese postmenopausal women were due to the increased fat mass and E2 production in adipose tissue (Reference Gruber, Tschugguel and Schneeberger35)