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Khanna, S., Atalay, M., Laaksonen, D

The peptide primarily activates melanocortin receptor subtypes MC1R, MC3R, MC4R, and MC5R, with particular affinity for MC3R and MC4R at therapeutic doses

This treatment removes dead skin cells accumulated over the face

patients with these features should be strongly suspected of having MC4R -deficient obesity, and genetic evaluation should be considered

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Strategic funding should prioritize translational research that links fundamental discoveries in immunology and stem cell biology with clinical application, while also supporting the robust clinical trial infrastructure necessary to test these advanced therapies