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Significant mean changes from baseline in 15-min post-exercise BL at week 9 were seen in the LCR group (-1.60 mmol/L, 95% CI -2.44, -0.75) but not in the PLA group (0.04 mmol/l, 95% CI -0.83, 0.92)

Helpful preparation steps include: carrying medication in original packaging keeping a copy of the prescription bringing slightly more medication than needed in case of delays Some travellers also carry a brief letter from their doctor explaining that the medication is prescribed for medical use

The gradual titration is designed to allow the body to adjust to GLP-1 receptor activation and minimize gastrointestinal side effects during the initial treatment period

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