retatrutide trial dosing just posted the biggest weight-loss numbers ever recorded for a drug — 28.3% (≈70 lb) average in Phase 3, with 45% of people hitting 30%+ loss, territory once reserved for bariatric Cagrilintide vs Retatrutide Compared |

Muscle Preservation Focus GLP-1 medications can cause muscle loss if not managed properly

Facing increasing revenue pressures, the state expects to save $17 million per year from the move

GLP-1RAs alleviate vascular aging under chronic stress via increasing adiponectin (APN) levels and inhibiting aortic MMP-9 and MMP-2 expression in ApoE -/- mice [96, 149]

This step also screens for state eligibility, since Willow currently operates in only 34 states

We were quite excited by the findings, as this study was the first to demonstrate a physiological role of GLP-1 in appetite control and energy intake in humans

Liraglutide reverses pronounced insulin-associated weight gain, improves glycaemic control and decreases insulin dose in patients with type 2 diabetes: a 26 week, randomised clinical trial (ELEGANT)