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Most believe the disorder springs from a complex interplay of genetics and environmental factors

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A study in C57BL/6 mice with intragastric administration of allulose at doses of 1 and 3 g per kg body weight described an increased GLP-1 secretion and a transient reduction in food intake that was no longer observed when animal lacking a GLP-1 receptor were used (Reference Hayakawa, Hira and Nakamura16)

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