The search terms used included GLP-1 agonists, Glucagon-Like Peptide-1 Receptor Agonists, semaglutide, Ozempic, Wegovy, liraglutide, bone health, orthopedic surgery, arthroplasty, post-operative complications, complications, bone health, bone strength, osteogenesis, and bone metabolism. To ensure the relevance and quality of the studies, we established specific inclusion and exclusion criteria
They work through multiple pathways to combat non-alcoholic fatty liver disease (NAFLD) and have shown promising results in resolving non-alcoholic steatohepatitis (NASH)
24 JAMA Internal Medicine report says that popular GLP-1s need to be rebranded from weight loss drugs to weight management drugs since some people may need to take them indefinitely
J Multidiscip Healthc
When combined with insulin or sulfonylureas, GLP-1 agonists may increase the risk of hypoglycemia, requiring dose adjustments of these medications
Efficacy and safety of once-weekly semaglutide monotherapy versus placebo in patients with type 2 diabetes (SUSTAIN 1): a double-blind, randomised, placebo-controlled, parallel-group, multinational, multicentre phase 3a trial