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N-acetylglucosamine-6-O sulfation on intestinal mucins prevents obesity and intestinal inflammation by regulating gut microbiota

S.ZhuW.OrgE.et al (2015)

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This modification allows the peptide to bind to amylin receptor subtypes 1 and 3 in the brain, specifically in the area postrema of the hindbrain, producing sustained appetite reduction without the peaks and valleys that come with shorter-acting compounds

Nordio, M., Basciani, S., & Camajani, E