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Other glucagon-like peptide-1 (GLP-1) receptor agonists have also induced thyroid C-cell adenomas and carcinomas in male and female mice and rats at clinically relevant exposures
While this has not been conclusively demonstrated in humans, it remains a concern, especially in those with a personal or family history of thyroid cancer
FIGURE 6 Cellular Validation of the Specificity of GPX4 Activator To further evaluate the selectivity and specificity of compound 102 in a cellular context, we employed the cellular thermal shift assay (CETSA
Zhao B, et al
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