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It also appears to support angiogenesis and counteract the negative effects of corticosteroids on healing. However, despite over two decades of preclinical research, there is a paucity of clinical trials evaluating its use for musculoskeletal injuries in humans, and it remains unapproved for medical use by regulatory bodies. Collagen peptides do have human clinical data

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Sclerosing agents tested included 1% bichloride of mercury, 48 30% sodium chloride and 50% grape sugar, 49, 50 30% sodium salicylate, 51 50% to 60% calorose, 52, 53 and SM