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TNF Inhibitor Therapy for Psoriatic Arthritis As the beneficial effects of tumor necrosis factor (TNF) inhibitor therapy in rheumatoid arthritis (RA) became clear in the late 1990s, it was only a matter of time before interest grew in testing these agents in psoriatic arthritis (PsA), a disease widely perceived to have similar manifestations and pathophysiology

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Nature 483:345349