N.DargenioC.CastellanetaS.De GiacomoA.LaguardiaM.SchettiniF.et al (2023)
Nambiar A, Kellogg D 3rd, Justice J, Goros M, Gelfond J, Pascual R, Hashmi S, Masternak M, Prata L, LeBrasseur N, Limper A, Kritchevsky S, Musi N, Tchkonia T, Kirkland J (2023) Senolytics dasatinib and Quercetin in idiopathic pulmonary fibrosis: results of a phase I, single-blind, single-center, randomized, placebo-controlled pilot trial on feasibility and tolerability
Abstract Glutathione-mediated biotransformation in the liver is a well-known detoxification process to eliminate small xenobiotics, but its impacts on nanoparticle retention, targeting and clearance are much less understood than liver macrophage uptake, even though both processes are involved in liver detoxification
Self-inject into your mid-thigh quadriceps for easy access and safety, or ask someone to inject into your deltoid/shoulder, and ensure you're reaching muscle tissue, not just subcutaneous fat, for optimal results
Remember to choose a different area to inject each week
Nat Rev Immunol (2014) 14:923