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A1 noradrenergic neurons tonically inhibit sympathoexcitatory neurons of C1 area in rat brainstem

Dosage Increase every four weeks: Increased dosage can cause increased side effects

doi: 10.1111/bcp.13688

This 1.6:1 ratio of fat-to-lean mass loss compares favorably to other weight loss interventions and significantly exceeds the typical 2:1 or 3:1 ratios seen with caloric restriction alone

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