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The IGF-1 signaling pathway has been implicated in lifespan control across multiple species, and IGF1 LR3 allows for controlled manipulation of this pathway to study its effects on cellular senescence, tissue maintenance, and age-related functional decline

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They reflect the pharmacokinetic reality of oral peptide delivery

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1821 This dispelled initial concerns about the inferiority of oral ALA suggested by the findings of an RCT comparing induction therapy with IV ALA followed by oral ALA (1200 mg/day or 600 mg/day)

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