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In contrast, curcumin demonstrates preferential inhibition of COX-2 over COX-1

Daily treatment with CARN for 5 days before and after a single dose of MTX achieved 4.8-fold and 26.5-fold elevation in serum total carnitine and 3.57-fold and 22.6-fold elevation in serum-free carnitine level compared with control and MTX-MD groups, respectively

Nutraceuticals are distinct from dietary supplements, which primarily provide essential nutrients like vitamins, minerals, and amino acids to address dietary deficiencies (3)

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Abstract Valproic acid (VPA) is a broad-spectrum antiepileptic drug and is usually well tolerated, but rare serious complications may occur in some patients receiving VPA chronically, including haemorrhagic pancreatitis, bone marrow suppression, VPA-induced hepatotoxicity (VHT) and VPA-induced hyperammonaemic encephalopathy (VHE)

Measurements of plasma-free hemoglobin further confirmed that intravascular hemolysis was increased in these rats