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BBC Science Focus (2023)

On the one hand, TME immunomodulation can trigger macrophage polarization from alternately activated macrophages M2 to classically activated macrophages M1, offering intertumoral H 2 O 2 for the Fenton reaction (Zanganeh et al., 2016), which effectively generates ROS and triggers lipid peroxidation (Yang and Stockwell, 2016

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Green tea polyphenol epigallocatechin 3-gallate in arthritis: progress and promise