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Documentation of comorbidities if applicable, such as diabetes, hypertension, sleep apnea, or hormonal conditions

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Understanding the medication's actual effects on digestive function, safety considerations, and management of gastrointestinal side effects is essential for clinicians prescribing this increasingly common therapy

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2.1 Microglia As the resident immunocompetent cells of the CNS, microglia derive from embryonic yolk sac progenitors and maintain continuous parenchymal surveillance through dynamic process motility (Masuda et al., 2022