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Dissolve in sterile ultrapure water or PBS (pH 7.07.4). Due to its susceptibility to oxidation, prepare fresh working solutions under inert atmosphere where possible. Store reconstituted solution at 4C and use within 2448 hours; or aliquot and store at 80C for longer-term stability

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In addition, the multifunctional FN III9-10/12-14 greatly enhanced the regenerative effects of BMP-2 and PDGF-BB in a rat critical-size bone defect model [186]

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