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In the Phase 3 trials, nausea was reported by approximately 44% of patients on Wegovy (semaglutide 2.4 mg) and approximately 28% of patients on Zepbound (tirzepatide 15 mg) during dose titration, usually mild to moderate, and usually improving with time and dose stabilization

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Obesity is one factor that has "stalled progress in life expectancy," as it is linked to 70% of the leading causes of death in high-income countries, according to the researchers

Its mode of action involves suppressing oncogene expression and modifying telomerase activity, and a summary of telomerase-related studies is to be presented