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[1] [2] Semaglutide mimics the action of the naturally occurring hormone GLP-1, which is released from the intestine in response to food intake

Moreover, NAMPT activity is crucial for the beneficial effects of calorie restriction, including improved oxidative stress management, mitochondrial biogenesis, and metabolic adaptation, as reported in a study involving Sprague-Dawley rats 213

The existence of registered studies means the compound is being investigated

The resulting plasma aliquots were frozen in a refrigerator at 80 C until further measurements

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Statistical analysis Data were statistically analyzed using SPSS (version 19.0.1, Chicago, Illinois, USA) for Windows