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Nitric oxide (NO) in alleviation of heavy metal induced phytotoxicity and its role in protein nitration

However, in atretic follicles, FSH may activate autophagy via different signaling pathways, leading to granulosa cells degradation and triggering follicular atresia ( Overall, the role of autophagy in establishing the follicular pool and promoting follicular survival highlights its potential as a novel therapeutic target for addressing DOR in vulnerable populations, such as those exposed to chemotherapy, environmental toxins, or genetic disorders (Figure 3B)

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Nature Communications , 8 , 15773

Suleiman Al-Sabah, Kuwait University, Kuwait

Discovery and Characterization SLU-PP-332 was identified through medicinal chemistry efforts at Saint Louis University (hence "SLU" in the name) to develop selective ERR modulators