Based on these findings, the USA has contraindicated the use of liraglutide, dulaglutide, extended-release exenatide, and semaglutide in patients with a personal or family history of MTC and multiple endocrine neoplasia type 2
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9 This value can be further applied to estimate the inhibition constant (Ki), which reflects the ligands binding affinity, using a simple thermodynamic relationship
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