[DOI] [PubMed] [Google Scholar] 32.Perrone L, Mothes E, Vignes M, et al
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Pyruvic acid accumulates in the blood and is subsequently converted to lactic acid, with the potential development of lactic acidosis
The SURPASS trials monitored thyroid adverse events as a primary safety focus and found no statistically significant increase in thyroid nodule formation or other thyroid complications in tirzepatide-treated groups versus placebo or semaglutide
Post-Thyroidectomy Patients Generally safe if thyroid levels are controlled