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Secondary metabolic markers include fasting glucose, insulin sensitivity via HOMA-IR or glucose tolerance testing, body composition changes (DEXA scan or MRI for fat mass and lean mass distribution), mitochondrial respiration capacity via Seahorse analyzer, and serum markers like HbA1c for long-term glucose control

The reviewer WK declared a shared affiliation with the authors PK, KR, SD to the handling editor at the time of review

2025;17(6):e86527

cell proliferation

Tumour necrosis factor receptor 1 and hepatocyte regeneration in acetaminophen toxicity: a kinetic study of proliferating cell nuclear antigen and cytokine expression

The limitation of conventional treatment alone is that it relies entirely on the bodys natural healing rate without augmentation