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The Hippo transducer YAP/TAZ as a biomarker of therapeutic response and prognosis in trastuzumab-based neoadjuvant therapy treated HER2-positive breast cancer patients
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The placebo (withdrawal) group regained 6.9 percentage points of body weight over those 48 weeks, while the continuation group lost an additional 7.9 percentage points
Sensitivity analysis reveals the degree of robustness of the results as follows ( Supplementary Figures S3, S4 ): i) Primary outcome & secondary outcomes (nonfatal stroke, all-cause death, HF hospitalization): Excluding any single study did not alter the direction and magnitude of effects, confirming robustness
Forced inhibition of VAN GLP-1R+ fibers alleviates the feeding reduction mediated by CCK but does not affect appetite suppression induced by GLP-1R agonists, such as liraglutide
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