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The circadian rhythm is a 24-hour cycle that regulates various internal processes, including the sleep-wake cycle, body temperature, metabolism, and digestion

Journal of Assisted Reproduction and Genetics, 37 (10), 2377-2387

J Transl Med (2011) 9:81

A knowledgeable medical provider can customize dosing based on a patients age, health history, symptoms, goals, body composition, and response to therapy rather than using a one-size-fits-all approach