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Metabolic changes after stopping GLP-1 Research also shows that metabolic markers can shift after treatment ends

These numbers had never been observed with a pharmacological agent outside bariatric surgery making tirzepatide a genuine milestone in metabolic medicine

doi: 10.1016/j.phymed.2023.155137 51 TanJKMaciaLMackayCR

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It is possible that glutamine, by increasing GLP-1 levels, which mediate FM and body weight reduction or replace FM with muscle, improves body composition in diabetes mellitus [28]

doi: 10.1210/jc.2005-2847