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Although continuous treatment of park 13 flies with L-DOPA reduced the inherent oxidative stress consistent with previous results, the flies still showed considerably higher levels of oxidative radicals (Fig
It is estimated that PD affects at least 1% of the population over the age of 60 ( substantia nigra pars compacta
These findings suggest that PAGln, rather than TMAO, could have implications for the immune microenvironment in the context of gut microbiota-metabolite interactions
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In contrast, both the combination group ( P = 0.0438
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