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In general, patients do not feel anything, but some may feel a tinge of tingling

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Additional evidence suggests this compound may influence lipid metabolic pathways through PPAR activation, potentially promoting cholesterol efflux from macrophage foam cells and enhancing reverse cholesterol transport processes [6]

PMID: 8651585

Chronic GCGR activation should increase plasma glucose levels and insulin levels would then need to rise to promote normoglycaemia during tri-agonist treatment, but this is not the case