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It is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist, which enhances insulin sensitivity and regulates appetite signals in the brain

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Given GH/IGF-1 axis involvement in neural tissue maintenance, researchers have investigated Tesamorelin in models examining hippocampal neurogenesis markers, cognitive performance endpoints, and amyloid-related pathway markers in aging animal models

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GLP-1 RAs have become cornerstone therapies for obesity and T2DM