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Zepbound is the only dual-action GLP-1/GIP medication approved for weight management, with the highest average weight loss in clinical trials (22%)

The transition to branded weight loss medications like Wegovy or Zepbound typically takes a few weeks, but the exact duration can vary depending on individual factors

Yet there still is no data on the long-term psychological impacts of the medication because just two studies have been conducted on teens, and there are no long-term follow-ups

In isolated rat islets, GLP-1 acts as a growth factor in a dose-dependent manner to increase the incorporation of tritiated thymidine and promotes cell proliferation through the upregulation of PI3K-mediated pathways (Sjholm, 1996