An antibody targeting the type I insulin-like growth factor receptor enhances the castration-induced response in androgen-dependent prostate cancer
Leading in the GLP-1 agonist diabetes arena are Eli Lillys recently approved Mounjaro (tirzepatide) and Novo Nordisks Ozempic (semaglutide), which has been a top seller for Novo since it first launched in 2017
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4 In STEP 2, which compared doses in adults with obesity and type 2 diabetes, the 2.4 mg dose produced an average weight loss of 9.6% over 68 weeks, compared with 3.4% on placebo
Specific situations warranting medical discussion include: Sudden or marked decrease in sexual desire that affects quality of life or relationships New onset of erectile dysfunction or difficulty achieving or maintaining arousal Changes in menstrual patterns, particularly irregular periods or amenorrhea Symptoms suggesting hormonal imbalance, such as fatigue, mood changes, or hot flashes Sexual dysfunction accompanied by other concerning symptoms like depression, severe fatigue, or relationship distress Any sexual health changes that cause significant personal concern, regardless of severity Seek immediate medical attention for these urgent symptoms: Severe, persistent abdominal pain (possible pancreatitis) Right upper quadrant pain with fever or yellowing of skin/eyes (possible gallbladder disease) Sudden vision changes (possible retinopathy complications) Signs of dehydration or decreased urination (possible acute kidney injury) New or worsening depression or suicidal thoughts (particularly with Wegovy) Your healthcare provider can conduct a thorough assessment to identify potential contributing factors
