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Glucocorticoid Receptor beta Overexpression Has Agonist-Independent Insulin-Mimetic Effects on HepG2 Glucose Metabolism

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Detected P-NA is in direct proportion to caspase-3 concentration

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The L subunit, being relatively distant from the active site (25 ), does not obstruct ligand entry and is considered not to affect the binding of ligands to the dicopper center 60

PIP3 recruits PDK1 and Akt to the membrane, where PDK1 phosphorylates and activates Akt