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We downloaded these regions as fasta files from NCBI, re-annotated them with Prokka (v.1.14.6) 54 and used Clinker 55 and Gene Graphics 56 for calculating pairwise sequence similarity and for visualization

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For men who do not respond to oral medications, second-line treatments include vacuum erection devices, intracavernosal injections (alprostadil), intraurethral therapy, or penile prosthesis surgery

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14 Moreover, Various lifestyle factors may affect endometriosis risk by potentially reducing inflammation