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Heat and UV degradation: The Cu2+-peptide bond undergoes hydrolysis at elevated temperatures (above 40 degrees Celsius, accelerated above 60 degrees C) and UV irradiation generates free radicals that can attack the peptide backbone

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2 h pretreatment followed by 12 h cadmium exposure) dose-dependently inhibits cadmium-induced oxidative stress in PC12 cells by reducing ROS and lipid peroxidation levels, restoring antioxidant enzyme activity, and maintaining intracellular GSH homeostasis [4]

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