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67 It is, however, intriguing to observe that in gut pathologies, especially related to the colon and including chronic inflammatory conditions, claudin-1 protein expression is markedly upregulated (and mislocalized)

Goldstein, PhD (Thymosin Beta-4/TB-500 Primary Investigator) Department of Biochemistry and Molecular Medicine (Emeritus) George Washington University School of Medicine and Health Sciences, Washington, D.C