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En 1902, Eugne Opie donne un rle prdominant une obstruction des voies biliaires par un calcul [1]

Breath tests use Carbon-13 labeled radioisotopes and the early arrival of an increased quantity of Carbon-13 compared to Carbon-12 that is measured in the breath gives an indication of how early or delayed ingested food particles containing these nuclear carbon atoms is being measured

There is no controlled human data confirming or quantifying this effect

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