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At this dose, colon tissues showed minimal inflammatory changes, focal ulceration, mucosal necrosis, and submucosal edema and hyperemia, alongside a greater restoration of crypt architecture and epithelial alignment (Figure 7)

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Mei Z, Cai C, Luo S, et al

850 The metabolic regulator sestrin 2 alleviates ferroptosis caused by intestinal I/R injury by activating the Keap1/Nrf2 signaling pathway