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In addition to prevention of apoptosis, myricetin reduces the HG-induced increase in lipid peroxidation levels, Bax and Bcl-2 expression levels, cleaved caspase-3 levels, suggesting that myricetin significantly lowers the risk of T2DM progression through protection of endothelial cells (43)

Med Mal Metab 17:4957 Enebo LB, Berthelsen KK, Kankam M, Lund MT et al (2022) Safety, tolerability, pharmacokinetics, and pharmacodynamics of concomitant administration of multiple doses of cagrilintide with semaglutide 2.4 mg for weight management: a randomised, controlled, phase 1b trial

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